2021-05-19 09:20 Pulmonary neutrophilia is a consistent finding in diseases such as human adult respiratory distress syndrome (ARDS), cystic fibrosis (CF), and in chronic obstructive pulmonary disease (COPD). It has been hypothesized that the pulmonary recruitment and activation of neutrophils contribute to the observed dysfunctional symptoms, including increased airway reactivity, the presence of pulmonary fibrosis, and the hypersecretion of mucus. Herein, Creative Biolabs provides LPS-induced mouse and rat models for researchers to investigate the effect of targeting mechanisms related to neutrophil recruitment and mediator release.
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