2021-08-25 13:58 It has been proven that antibody therapy is highly powerful for cancer treatment. Antibody-dependent cell-mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC) are two important cell killing mechanisms of antibody drugs. Besides, for certain therapeutic bispecific IgGs and Fc-containing bispecific antibodies (BsAbs), ADCC is very important for their in vivo efficacy. To test if therapeutic BsAb candidates can efficiently induce ADCC, various ADCC assays are employed. Creative Biolabs provides various ADCC assays for the functional analysis of bispecific antibodies. Abiding the strict quality standards, Creative Biolabs assures the efficacy profiles of the therapeutic antibodies for customers.
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