2021-04-02 06:19 Polysaccharides from pathogenic bacteria can be made more immunogenic by chemical conjugation of them to carrier proteins. Such method produces a vaccine that effectively induces an immune response to the conjugated polysaccharide. This approach is a very important breakthrough for pediatric polysaccharide vaccines because, unlike adults, young children lack the ability to produce a protective immune response when the polysaccharide fraction itself is used. The discovery that polysaccharides conjugating to carrier proteins enhances immunogenicity and converted a T-cell independent to T-cell dependent antigens was one of the most important contemporary achievements in vaccinology, heralding a new era in vaccine development. In terms of the extensive experience in conjugate vaccine research, Creative Biolabs is proud to offer our customers professional design services and a series of carrier proteins with the best quality and most competitive price.
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