2021-08-26 06:24 The quality of X-ray diffraction data of the protein crystal can determine the success rate of the subsequent steps of structure determination and the reliability of the reconstructed three-dimensional (3D) structural model. After successfully obtain ... дальше
2021-08-26 06:24 The necessary condition for successful X-ray crystallographic analysis is to obtain a single crystal of the target protein that meets the X-ray diffraction standard. The data are then collected by X-ray diffraction from a single crystal with an order ... дальше
2021-08-26 06:24 Because most viruses are small (< 200 nm), standard optical microscopes are generally not suitable for direct observation of them. The use of electron microscopy (EM) to visualize the ultrastructure of viruses has become the gold standard for vira ... дальше
2021-08-26 06:24 Scanning electron microscopy (SEM) is characterized by simple sample preparation, wide adjustable magnification range, high image resolution, and large depth of field. SEM technology can scan the surface morphology of the sample by emitting a bright ... дальше
2021-08-26 06:23 The ultra-thin section electron microscopy (EM) technology is an effective means to observe the characteristics of viruses and the interaction between viruses and host cells. Creative Biostructure provides ultra-thin section EM services combined with ... дальше
2021-08-26 06:23 The ongoing outbreak of novel coronavirus (also termed as SARS-CoV-2) poses a challenge for public health. There is an urgent need to understand the molecular mechanism of this viral infection and to develop effective vaccines and antiviral drugs on ... дальше
2021-07-21 10:59 Isothermal titration calorimetry (ITC) is widely used to detect the affinity and enthalpy of interactions between proteins and/or other molecules. In addition, the quantitative nature of ITC is useful in the characterization of recombinant proteins, ... дальше
2021-07-21 10:59 Creative Biostructure provides comprehensive services for the study on the interaction of biological macromolecules such as proteins involved in coronavirus research. Similar to surface plasmon resonance (SPR), bio-layer interferometry (BLI) is also ... дальше
2021-07-21 10:58 Creative Biostructure is a leading service supplier in the field of structural biology with a team of specialists specializing in contract research services for basic and preclinical research related to coronavirus infection. Currently, we have estab ... дальше
2021-07-21 10:58 The three-dimensional (3D) reconstruction technology of single-particle cryo-electron microscopy (cryo-EM) involves a complex image processing process from two-dimensional (2D) projection images to a 3D reconstruction model. Creative Biostructure cur ... дальше