2021-04-22 21:36
Under physiological condition, most protein-protein interactions are transient, and happen in a very short duration, which make them difficult to be studied. Crosslinking reagents, or crosslinkers, provide the analytical solution to capture protei
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2021-04-22 21:36
Co-immunoprecipitation, Co-IP in short, is a widely applied technique to identify physiologically-relevant protein-protein interactions by utilizing target protein-specific antibodies to indirectly capture proteins that are bound to this specific tar
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2021-04-22 21:36
The aim of comprehensive peptidomics, is not only to identify and validate all endogenous peptides in a biological sample under investigation, but also to compare expression levels of the peptides of interest for specific biochemical processes. Thus,
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2021-04-02 06:42
Phenolic acids, also known as phenolcarboxylic acids, are types of aromatic acid compound. They are also a subclass of a larger category of metabolites commonly referred to as “phenolics”. The term phenolics consists of approximately 8000 natural
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2021-04-02 06:41
Mevalonic acid (MVA) is an important organic compound in biochemistry. The name is a contraction of dihydroxymethylvalerolactone. The carboxylate anion of mevalonic acid, which is the predominant form in biological environments is called mevalonate,
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2021-04-02 06:41
Isoprostanes are a newly discovered class of compounds formed in vivo as a consequence of non-enzymatic oxidation of polyunsaturated fatty acids. The isoprostanes produced by free radical-catalyzed peroxidation of arachidonic acid, so called F2-is
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2021-04-02 06:41
Ketone bodies refer to three molecules, acetoacetate (AcAc), 3-hydroxybutyrate (3HB) and acetone. 3HB is formed from the reduction of AcAc in the mitochondria. These two predominant ketone bodies are energy-rich compounds that transport energy fr
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2021-04-02 06:41
Nucleotide sugars are the activated forms of monosaccharides. Nucleotide sugars act as glycosyl donors in glycosylation reactions. Those reactions are catalyzed by a group of enzymes called glycosyltransferases. To act as glycosyl donors, those monos
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2021-04-02 06:41
A branched-chain amino acid (BCAA) is an amino acid having aliphatic side-chains with a branch (a central carbon atom bound to three or more carbon atoms). Among the proteinogenic amino acids, there are three BCAAs: leucine, isoleucine and valine. No
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